HIGHLIGHTS
- who: Jörg Weiske from the (UNIVERSITY) have published the research work: The Histidine Triad Protein Hint1 Triggers Apoptosis Independent of Its Enzymatic Activity*, in the Journal: (JOURNAL) of September/15,/2006
- how: In this respect the authors investigated whether the enzymatic activity of Hint1 is required to trigger apoptosis.
SUMMARY
The authors have found that, after transient transfection with Hint1, SW480 and MCF-7 cells undergo apoptosis as analyzed by pro-caspase-3 and poly(ADP-ribose) polymerase cleavage, M30 CytoDEATH staining, cytochrome c release, and DNA fragmentation enzyme-linked . . .
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