The histone deacetylase inhibitor i13 induces differentiation of m2, m3 and m5 subtypes of acute myeloid leukemia cells and leukemic stem-like cells

HIGHLIGHTS

• who: Xiangyu Ma from the School of Pharmacy, Weifang Medical University, Weifang, China, Department of Pharmaceutical Sciences, College of have published the article: The Histone Deacetylase Inhibitor I13 Induces Differentiation of M2, M3 and M5 Subtypes of Acute Myeloid Leukemia Cells and Leukemic Stem-Like Cells, in the Journal: (JOURNAL)
• what: The authors provided the first demonstration that I13 exhibited differentiation-inducing activity in AML cell lines.
• how: The above results indicated that I13 inhibits the proliferation of Kasumi-1 KG-1 MOLM-13 and NB4 cells which is not associated with cell . . .
  

   

  

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