The hnrnpk/a1/r/u complex regulates gene transcription and translation and is a favorable prognostic biomarker for human colorectal adenocarcinoma

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SUMMARY

    This protein is a conserved pre-mRNA-binding protein that is involved in multiple processes of gene_expression, including chromatin remodeling, transcription, and mRNA_splicing, translation, and stability. The Tumor Immune Estimation Resource (TIMER2.0) (http:// timer.cistrome.org/) is a public webtool for comprehensive assessments of abundance of tumor-infiltrating immune cells (TIICs) according to gene_expression profiles. The authors mainly performed hnRNPK expression in tumors and the correlation between gene_expression and abundance of immune infiltrates, involving B cells, CD8+ T_cells, and CD4+ T_cells, macrophages, neutrophils, dendritic cells (DCs), compared with purity in tumors. Abnormal gene_expressions . . .

     

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