HIGHLIGHTS
- who: November et al. from the Boston University, United States have published the paper: The human cytomegalovirus decathlon: Ten critical replication events provide opportunities for restriction, in the Journal: (JOURNAL)
- how: Together this work definitively shows that the vAC acts as a hub to coordinate efficient virion assembly and egress by remodelling host membranes and the secretory system.
- future: More work is needed to solve this intricate mechanism of replication initiation. There is no definitive evidence of any host proteins that mediate envelopment of HCMV virions but future work may yet uncover examples . . .
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