The human ll-37(17-29) antimicrobial peptide reveals a functional supramolecular structure

HIGHLIGHTS

  • who: Yizhaq Engelberg from the Israel Institute have published the article: The Human LL-37(17-29) antimicrobial peptide reveals a functional supramolecular structure, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
  • what: The authors demonstrate that the active core peptide of hLL-37, containing residues 17-19 (hLL-3717-29), formed supra-helical highly stable fibrils that interact with bacterial cells. Links between fibril formation and antimicrobial activity are accumulating11-14,17-21,54, and here, the authors provide atomic-level insight for such example.

SUMMARY

    Although not directly detected in_vivo . . .

     

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