HIGHLIGHTS
- who: Carolina Martín-Sánchez from the (UNIVERSITY) have published the Article: The human-specific duplicated α7 gene inhibits the ancestral α7, negatively regulating nicotinic acetylcholine receptor-mediated transmitter release, in the Journal: (JOURNAL) of October/22,/2020
- what: The authors examine the brain function of one of these genes (CHRFAM7A) and its product (dupα7 subunit). The authors characterize that role by combining immunoblotting, quantitative RT-PCR and FRET techniques with functional assays of α7-nAChR activity using human neuroblastoma SH-SY5Y cell variants with different dupα7 expression levels. The subsequent experiments . . .
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