The identification of small molecule inhibitors of the plant inositol phosphorylceramide synthase which demonstrate herbicidal activity

HIGHLIGHTS

• who: Elizabeth C. Pinneh from the Department of Biosciences, Durham University, Durham, LE, UK Department of Chemistry, Durham have published the paper: The identification of small molecule inhibitors of the plant inositol phosphorylceramide synthase which demonstrate herbicidal activity, in the Journal: Scientific Reports Scientific Reports of 17/05/2019
• how: In this study the well characterized Arabidopsis thaliana enzyme AtIPCS220 the most highly expressed of the 3 IPCS isoforms33 was used to complement S. cerevisiae lacking AUR1. The most potent selective compound was tested in_vivo against seedlings and demonstrated herbicidal activity. Initially all 106 selective . . .
  

   

  

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