The immune microenvironment in multiple myeloma: friend or foe?

HIGHLIGHTS

  • who: Raquel Lopes et al. from the Faculty of Medicine, University of Lisbon, Lisbon, Portugal have published the paper: The Immune Microenvironment in Multiple Myeloma: Friend or Foe?, in the Journal: Cancers 2021, 13, 625. of /2021/
  • what: The present review considered the role of the BM immune microenvironment during MM progression when, undeniably, immune cells become myeloma's best friends.

SUMMARY

    While myeloma cells promote MDSCs development and survival, MDSCs create a protective environment by inducing NK T and CD8+T_cells anergy. This phenomenon induces MDSCs expansion in_vitro and enhances . . .

     

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