The impact of glucose on mitochondria and lifespan is determined by the integrity of proline catabolism in c. elegans

HIGHLIGHTS

  • who: Xi Feng from the School of Life, Chongqing University, Chongqing, China have published the Article: The impact of glucose on mitochondria and lifespan is determined by the integrity of proline catabolism in C. elegans, in the Journal: (JOURNAL)
  • what: The authors demonstrate that this crosstalk between proline and glucose catabolism is mediated by the transcription factor DAF-16. The authors propose that dietary glucose levels may play a crucial role in determining the therapeutic efficacy for human disorders associated with faulty or altered proline catabolism.
  • how: Next the authors investigated whether the . . .

     

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