The impact of non-enzymatic reactions and enzyme promiscuity on cellular metabolism during (oxidative) stress conditions

HIGHLIGHTS

  • who: Gabriel Piedrafita and collaborators from the Department of Biochemistry, University of Cambridge, Tennis Court Rd, The Francis Crick Institute, Mill Hill Laboratory, The Ridgeway, London , AA, UK have published the research work: The Impact of Non-Enzymatic Reactions and Enzyme Promiscuity on Cellular Metabolism during (Oxidative) Stress Conditions, in the Journal: Biomolecules 2015, 5, 2101-2122 of 10/09/2015
  • future: Termed the glycolysis/PPP transition the oxidative part of the pentose_phosphate_pathway (PPP) that is more redox resistant increases in activity resulting in enhanced NADPH production under the conditions where this cofactor is required . . .

     

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