HIGHLIGHTS
- who: Ola Habanjar and collaborators from the Université Clermont-Auvergne, INRAE, UNH, ECREIN, f, Clermont-Ferrand, France have published the Article: The Impact of Obesity, Adipose Tissue, and Tumor Microenvironment on Macrophage Polarization and Metastasis, in the Journal: (JOURNAL)
- how: Hereby this review describes the cellular and molecular mechanisms that link inflammation obesity and cancer.
SUMMARY
This concept describes the dependence of cancer metastasis on tumor cells (seeds) and its complex interactions with the tumor microenvironment (TME) (soil). In primary tumors, macrophages can stimulate angiogenesis and improve tumor cell motility and . . .
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