The impact of p-glycoprotein on opioid analgesics: what’s the real meaning in pain management and palliative care?

HIGHLIGHTS

• who: Flaminia Coluzzi and colleagues from the Department Medical and Surgical Sciences and Biotechnologies, Sapienza University of Rome, Polo Pontino, Latina, Italy have published the paper: The Impact of P-Glycoprotein on Opioid Analgesics: Whatu2019s the Real Meaning in Pain Management and Palliative Care?, in the Journal: (JOURNAL)
• what: In the review the authors explore the interactions between P-gp and opioidergic drugs with their implications in clinical practice.
• how: Similar results were obtained with verapamil and lopinavir/ritonavir towards fexofenadine AUC and are attributed to a mild P-gp induction in the . . .
  

   

  

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