The importance of pore-forming toxins in multiple organ injury and dysfunction

HIGHLIGHTS

• who: Simon T. Abrams and colleagues from the Department of Clinical Infection, Microbiology and Immunology, University of Liverpool, Liverpool , BE, UK have published the article: The Importance of Pore-Forming Toxins in Multiple Organ Injury and Dysfunction, in the Journal: Biomedicines 2022, 3256 of /2022/
• what: This work has confirmed the importance of pore-forming toxins in the development of MODS and proposed a potential mechanism to explain the reversibility of MODS. The authors will investigate whether cell membrane disruption by both endogenous (extracellular histones) and exogenous (pneumolysin) pore-forming toxins contribute to multiple organ . . .
  

   

  

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