The increased frequency of type 1 regulatory t (tr1) cells and the altered expression of aryl hydrocarbon receptor (ahr) and interferon regulatory factor-4 (irf4) genes in type 1 diabetes: a case-control study

HIGHLIGHTS

• What: Materials And Methods Study design and subjects A case-control design was employed for this study, which was conducted between 2023 and 2024. Significance was set at p and amp;lt; 0.05 AHR, aryl hydrocarbon receptor; IRF4, interferon regulatory factor-4; SEM, standard error of the mean; T1DM, type 1 diabetes_mellitus Frequency of Tr1 cells in T1DM patients compared to the healthy controls Flow cytometry analysis was conducted to determine the proportion of Tr1 cells in PBMCs from individuals with T1DM and healthy controls. To address these gaps, the study aimed to investigate the associations . . .
  

   

  

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