The influence of microrna-31 on oxidative stress and radiosensitivity in pancreatic ductal adenocarcinoma

HIGHLIGHTS

  • who: Jason McGrath et al. from the (UNIVERSITY) have published the research: The Influence of MicroRNA-31 on Oxidative Stress and Radiosensitivity in Pancreatic Ductal Adenocarcinoma, in the Journal: Cells 2022, 11, x FOR PEER REVIEW of 18/05/2022
  • what: The authors investigated the role and potential mechanisms linking miR-31 to PDAC radioresistance. The study demonstrates for the first time that manipulating miR-31 alters GPx8 expression regulating ROS detoxification and promoting either a radioresistant or radiosensitive phenotype. The authors demonstrate miR-31 as a suitable therapeutic target in PDAC through the regulation . . .

     

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