The influence of tissue spatial geometry and functional organisation on liver regeneration

HIGHLIGHTS

  • who: Luigi Aloia from the MRC Laboratory for Molecular Cell Biology, University College London, Gower Street, London WC E BT, UK have published the paper: The influence of tissue spatial geometry and functional organisation on liver regeneration, in the Journal: (JOURNAL)
  • what: How do ECM remodelling and increased stiffness in the damaged liver influence the epithelial_cells at the molecular level?
  • how: The data indicated that ~15% of adult mature cholangiocytes isolated from the mouse healthy liver can acquire a bipotent progenitor state when grown as organoid cultures .
  • future: Work is needed . . .

     

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