The insulin receptor substrate 1 (irs1) in intestinal epithelial differentiation and in colorectal cancer

HIGHLIGHTS

  • who: Reza Malekzadeh and collaborators from the Unit of General Pathology, Aging Research Center, Gd`Annunzio University Foundation, Chieti, Italy, Department of Medical, Oral and Biotechnological Sciences, G have published the research: The Insulin Receptor Substrate 1 (Irs1) in Intestinal Epithelial Differentiation and in Colorectal Cancer, in the Journal: (JOURNAL) of April/27,/2012
  • what: The authors investigated the expression, localization and clinicopathologic correlations of IRS1 ex vivo, in canceruninvolved human colonic epithelium, primary CRCs and paired liver metastases, and in_vitro, in two CRC cell models capable of spontaneous in_vitro polarization, Caco2 and HT29 .
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