The integrative analysis of competitive endogenous rna regulatory networks in osteoporosis

HIGHLIGHTS

  • who: Hao Li from the DepartmentMedical University have published the research work: The integrative analysis of competitive endogenous RNA regulatory networks in osteoporosis, in the Journal: Scientific Reports Scientific Reports
  • what: By employing a comprehensive strategy of bioinformatics analysis and experimental verification, we constructed a circRNA-miRNA-mRNA network and found that hsa_circ_0028877, hsa_circ_0082916, hsa_circ_0030712, DIRAS2, CAMK2A, and MAPK4 were significantly correlated with osteogenesis, and the axis of hsa_circR_0028877/hsa-miR-1273f/CAMK2A and hsa_circR_0028877/hsa-miR-1273f/DIRAS2 might function as ceRNA mechanisms to exert critical roles in osteoporosis.
  • how: The volcano . . .

     

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