The interaction between autophagy and the epithelial-mesenchymal transition mediated by nicd/ulk1 is involved in the formation of diabetic cataracts

HIGHLIGHTS

  • who: Jiyuan Ma from the Department of Ophthalmology, Eye Institute of PLA, Xijing Hospital, Fourth Military Medical University, West Changle Road, Xi`an, Shaanxi, People`s Republic of China have published the article: The interaction between autophagy and the epithelial-mesenchymal transition mediated by NICD/ULK1 is involved in the formation of diabetic cataracts, in the Journal: (JOURNAL)
  • what: We have showed that a high glucose concentration induces the EMT through the Jagged1/Notch1/ NICD/Snail signaling pathway and inhibits autophagy through the AKT/mTOR/ULK1 pathway in LECs, and both processes may participate in . . .

     

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