The interaction efficiency of xpd-p44 with bulky dna damages depends on the structure of the damage

HIGHLIGHTS

  • who: Olga Lavrik from the Laboratory of Bioorganic Chemistry of Enzymes, Institute of Chemical and Fundamental Medicine SB RAS, Wuerzburg, Germany New York University, United States have published the article: The Interaction Efficiency of XPD-p44 With Bulky DNA Damages Depends on the Structure of the Damage, in the Journal: (JOURNAL)
  • what: The authors characterized the interaction of ctXPD and the ctXPD-ctp44 complex with model DNA substrates, which contained bulky damages in the translocated strand. The data obtained in this work have shown that the affinity of ctXPD-ctp44 for ss-nFlu-DNA (EC50 . . .

     

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