The intermicrovillar adhesion complex in gut barrier function and inflammation

HIGHLIGHTS

  • who: Bernadette Mu00f6dl and collaborators from the Center for Cancer Research, Medical University of Vienna and Comprehensive Cancer Center, Vienna, Austria have published the research: The intermicrovillar adhesion complex in gut barrier function and inflammation, in the Journal: (JOURNAL)

SUMMARY

    Identified risk genes are expressed in different types of intestinal epithelial_cells as well as in innate and adaptive immune cells indicating complex epithelial-immune interactions. Besides the actin-bundling proteins, several proteins of the ezrin, radixin, moesin (ERM), and myosin (MYO) families are required for microvillus stabilization as they connect the actin core . . .

     

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