HIGHLIGHTS
- who: Paul Huchedu00e9 and colleagues from the Department of Pediatric Oncology, Institut d`Hematologie et d`Oncologie Pu00e9diatrique, Centre, Lyon, France have published the Article: The Intricate Epigenetic and Transcriptional Alterations in Pediatric High-Grade Gliomas: Targeting the Crosstalk as the Oncogenic Achillesu2019 Heel, in the Journal: Biomedicines 2022, 10, 1311. of /2022/
- what: The authors describe how the disruption of the epigenetic landscape in a specific permissive transcriptional context ultimately leads to pediatric gliomagenesis. The authors propose that transcriptional network alterations reflect the co-option of developmental processes and act in an intricate interplay . . .
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