The juggernaut of adaptive metabolism in cancers: implications and therapeutic targets

HIGHLIGHTS

  • who: Samson Mathews Samuel and collaborators from the (UNIVERSITY) have published the research: The Juggernaut of Adaptive Metabolism in Cancers: Implications and Therapeutic Targets, in the Journal: Cancers 2022, 5202 of 20/Oct/2022
  • what: The review focused on the specific role of hypoxiainducible factor 1 (HIF-1), a hypoxia-induced transcription factor, and its crosstalk with various enzymes and regulatory aspects of glucose metabolism in cancers, discussing the efficacy of several HIF-1 inhibitors in inhibiting cancer cell proliferation and survival .

SUMMARY

    Unlike previous notions, it is evident that, apart . . .

     

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