The kappa opioid receptor agonist u50,488h did not affect brain-stimulation reward while it elicited conditioned place aversion in mice

HIGHLIGHTS

  • who: Peng Huang from the (UNIVERSITY) have published the research work: The kappa opioid receptor agonist U50,488H did not affect brain-stimulation reward while it elicited conditioned place aversion in mice, in the Journal: (JOURNAL)
  • what: The current and previous results from our lab revealed that using the mouse ICSS test to assess anhedonic effects of U50,488H has yielded inconsistent results.
  • how: When the current data were presented the same way no difference was found between saline- and U50488Htreated groups of mice (115.9 ± 3.5 vs 119.5 ± 4.8 . . .

     

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