HIGHLIGHTS
- who: rdserver1 from the University of, University of Chinese of Sciences, No A Yuquan Road, Beijing, China have published the Article: The ketone body acetoacetate activates human neutrophils through FFAR2, in the Journal: (JOURNAL)
- what: This study shows that BHB directly inhibits activation of the NLRP3 inflammasome, resulting in a reduced release of the pro-inflammatory cytokines IL-1u03b2 and IL-18 . The authors explored the ability of human FFAR2 to sense acetoacetate and the impact of this recognition in regulating human neutrophil functions. The authors demonstrate that human FFAR2 senses not only short chain . . .
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