The landscape of chimeric antigen receptor t cell therapy in breast cancer: perspectives and outlook

HIGHLIGHTS

  • who: Hao Zhang from the Jackson Laboratory, United States Department of Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science have published the paper: The landscape of chimeric antigen receptor T cell therapy in breast cancer: Perspectives and outlook, in the Journal: (JOURNAL)
  • what: This study demonstrated that CAR-T_cells can effectively overcome antibody therapy failure by masking the tumor epitope and blocking the tumor stroma revolutionized the mainstream treatment concept for HER2positive breast cancer.
  • how: In this review the authors introduced the novel CAR-T_cell engineering strategy summarized the potential targets . . .

     

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