The landscape of tumor cell states and spatial organization in h3-k27m mutant diffuse midline glioma across age and location

HIGHLIGHTS

• who: Ilon Liu from the (UNIVERSITY) have published the research: The landscape of tumor cell states and spatial organization in H3-K27M mutant diffuse midline glioma across age and location, in the Journal: (JOURNAL) of 28/Oct/2021
• what: The authors show that stem-like oligodendroglial precursor-like cells, present across all clinico-anatomical groups, display varying levels of maturation dependent on location. Collectively, the study provides a powerful framework for rational modeling and therapeutic interventions. The authors aimed at delineating and comparing transcriptional heterogeneity within the cohort stratified by age and location (Fig 1c . . .
  

   

  

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