HIGHLIGHTS
- who: Adam Roberts and collaborators from the Medicine, Cornell University, Hinxton, Cambridge, United Kingdom have published the research: The Leishmania donovani Ortholog of the Glycosylphosphatidylinositol Anchor Biosynthesis Cofactor PBN1 Is Essential for Host Infection, in the Journal: (JOURNAL) of 07/06/2022
- what: The authors show that this phenotype is caused by the loss of glycosylphosphatidylinositol (GPI)-anchored surface molecules and that LdBPK_061160 encodes a noncatalytic component of the L donovani GPI-mannosyltransferase I (GPI-MT I) complex. The authors identified the enzyme required for an essential step in the GPI anchor-biosynthetic pathway in . . .
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