The limits of molecular signatures for pancreatic ductal adenocarcinoma subtyping

HIGHLIGHTS

• who: Lautizi and colleagues from the University of Southern Denmark have published the Article: The limits of molecular signatures for pancreatic ductal adenocarcinoma subtyping, in the Journal: (JOURNAL)
• what: The authors focus on the four transcriptomic and genomic studies most frequently discussed in literature for the stratification of PDAC into different groups. The authors seek to answer the question if it is possible to replicate the same subgroups in a cohort that is not the one used for signature discovery. The authors demonstrate that they are only indirectly, if it all, linked to cancer subtypes . . .
  

   

  

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