The long non-coding rna hoxa-as2 promotes proliferation of glioma stem cells and modulates their inflammation pathway mainly through post-transcriptional regulation

HIGHLIGHTS

  • who: Elisa Le Boiteux and colleagues from the Université Clermont Auvergne, CNRS, GReD, Clermont-Ferrand, FranceCNRS UMR, Institut Curie, PSL Research University and Paris-Saclay University have published the research: The Long Non-Coding RNA HOXA-AS2 Promotes Proliferation of Glioma Stem Cells and Modulates Their Inflammation Pathway Mainly through Post-Transcriptional Regulation, in the Journal: (JOURNAL) of 13/04/2022
  • what: This study focused on this major isoform.
  • how: Next the authors analyzed histone mark signatures relevant for promoter and/or enhancer activity (i.e. the permissive H3K4me3 active H3K27ac and repressive . . .

     

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