The long noncoding rna adipint regulates human adipocyte metabolism via pyruvate carboxylase

HIGHLIGHTS

• who: Alastair G. Kerr from the Karolinska Institute Karolinska University have published the research: The long noncoding RNA ADIPINT regulates human adipocyte metabolism via pyruvate carboxylase, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS of 25/09/2020
• what: Much of the work on lncRNAs has focused on how they regulate transcription through chromatin modifications, alter the nuclear architecture, and affect mRNA kinetics8. The authors show that perturbations in PC activity mirror the effects of ADIPINT perturbation on adipocyte lipid metabolism and the WAT expression of ADIPINT is closely linked to in_vivo metabolic phenotypes and PC . . .
  

   

  

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