The low and high doses administration of lutein improves memory and synaptic plasticity impairment through different mechanisms in a rat model of vascular dementia

HIGHLIGHTS

  • What: This study provides new finding that the treatment with a low and high dose of lutein improve spatial memory loss and long-term synaptic plasticity impairment in VD, but only administration of the high dose of lutein completely restores the fear memory, the hippocampal cell number and volume as well as MDA level.
  • Who: Hamideh Asadi nejad and collaborators from the Department of Physiology, The Medical School, Shiraz University of Medical Sciences, Shiraz, Iran have published the research: The low and high doses administration of lutein improves memory and synaptic plasticity impairment through different . . .

     

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