The lrrc8/vrac anion channel facilitates myogenic differentiation of murine myoblasts by promoting membrane hyperpolarization

HIGHLIGHTS

  • who: Lingye Chen from the (UNIVERSITY) have published the paper: The LRRC8/VRAC anion channel facilitates myogenic differentiation of murine myoblasts by promoting membrane hyperpolarization, in the Journal: (JOURNAL) of April/10,/2019
  • what: The authors report that the leucine-rich repeat containing family 8 (LRRC8)/volumeregulated anion_channel (VRAC) promotes mouse myoblast differentiation. The authors have investigated the role of VRAC in skeletal myogenesis using mouse C2C12 myoblasts. The authors show that consistent with a previous report , inhibition of the LRRC8A-containing anion_channel VRAC does not impair the proliferation of C2C12 myoblasts.
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