The machinery of exosomes: biogenesis, release, and uptake

HIGHLIGHTS

  • who: Sofia V. Krylova and Daorong Feng from the Departments of Medicine, Albert Einstein College of Medicine, New York, NY, USA have published the paper: The Machinery of Exosomes: Biogenesis, Release, and Uptake, in the Journal: (JOURNAL)

SUMMARY

    Early endosome, the initial vesicle generated by the plasma_membrane budding into the cell, is the first stop in the endosomal trafficking pathway; its role is to perform primary sorting and fate determination of the endocytosed cargo. Cargo that needs to be recycled will localize to the peripheral tubular domains of the endosomes, from where it . . .

     

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