The magic of small-molecule drugs during ex vivo expansion in adoptive cell therapy

HIGHLIGHTS

  • who: PI and collaborators from the University Hospital Fundaciou0301n Jimu00e9nez Du0131u00b4az, Spain have published the paper: The magic of small-molecule drugs during ex vivo expansion in adoptive cell therapy, in the Journal: (JOURNAL)

SUMMARY

    Adoptive T-cell therapy (ACT) is a form of cellular immunotherapy in which tumor-reactive T_cells recognize and eliminate malignant cells after infusion into patients. In the past few decades, cell-based therapies with chimeric antigen receptor (CAR) T_cells, engineered T_cell receptor (eTCR) T_cells, tumor-infiltrating lymphocytes (TILs), and other antigenspecific T_cells have rapidly developed and shown enormous . . .

     

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