The mammalian cysteine protease legumain in health and disease

HIGHLIGHTS

  • who: Rigmor Solberg and collaborators from the Section for Pharmacology and Pharmaceutical Biosciences, Department of Pharmacy, University of, Denmark, Odense, Denmark have published the research work: The Mammalian Cysteine Protease Legumain in Health and Disease, in the Journal: (JOURNAL)

SUMMARY

    In contrast, caspases prefer aspartate (Asp) in the substrate P1 position, and in P1 position, and in more acidic (pH and amp;lt; 4) caspase-like legumain achieves caspase-like protemore acidic conditions (pH and amp;lt; 4) conditions legumain achieves proteolytic activity. olytic.activity Thus, the of legumain is pH-dependent. Cystatins . . .

     

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