HIGHLIGHTS
- who: G. van der Elst et al. from the Heidelberg University, Germany have published the paper: The mast cell: A Janus in Kidney Transplants, in the Journal: (JOURNAL)
- what: In this manuscript the authors propose a model depicting the multifaceted contribution of mast cells in the setting of kidney transplantation, namely in tolerance, rejection and chronic damage/fibrosis. frontiersin.org 10.3389/fimmu.2023.1122409 transplant tolerance, is shown in Figures 1, 2. The model shows almost no inhibitory pathways, explaining the progressive state of fibrosis within KTx even when immunosuppressive drugs are taken. As . . .
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