HIGHLIGHTS
- who: Billy Hobbs from the School of Biosciences, University of Sheffield, Firth Court, Western Bank, Sheffield , TN, UK have published the research work: The measurement of binding affinities by NMR chemical shift perturbation, in the Journal: (JOURNAL)
- what: The authors show that chemical shift changes of individual residues can be fit to give residue-specific affinities. The authors show that the most reliable results are obtained by fitting all the shifts together, and that the affinities resulting from this method are considerably more precise and slightly stronger than those obtained by selecting peaks and fitting . . .
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