The mechanism of budding of retroviruses from cell membranes

HIGHLIGHTS

  • who: Andrew, Pincetic and Jonathan, Leis from the Department of Microbiology and Immunology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA have published the article: The Mechanism of Budding of Retroviruses from Cell Membranes, in the Journal: (JOURNAL) of 18/Dec/2008
  • what: The current model proposes that the M domain, located within the matrix regions of Gag, mediates plasma_membrane binding for assembly and budding.

SUMMARY

    Domain is used here to denote the amino_acid sequence that constitutes the biological function. Single amino_acid substitutions in the PPPY sequence in ASLV Gag . . .

     

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