The mechanism underlying redundant functions of the ythdf proteins

HIGHLIGHTS

  • who: Zhongyu Zou from the Department of Chemistry, The University of, USA have published the article: The mechanism underlying redundant functions of the YTHDF proteins, in the Journal: (JOURNAL)
  • what: The authors show that YTHDF1 and YTHDF2 differ in their low-complexity domains (LCDs) and exhibit different behavu2011 iors in condensate formation and subsequent physiological functions. Interrogating functions of YTHDF proteins only based on actively translated RNA may lead to incorporation of indirect effects in the analysis, especially when aiming to elucidate their roles in translation and decay. This study showed that individual mRNAs could . . .

     

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