HIGHLIGHTS
- who: Diana Ainembabazi from the Department of Medicine, School of Medicine, Joseph E, Indiana University, WWalnut St have published the article: The mechanistic role of cardiac glycosides in DNA damage response and repair signaling, in the Journal: (JOURNAL)
- what: The authors focus on the structural and functional differences of CGs toward identifying the critical features for targeting of these agents. This study showed activation of the checkpoint kinases (Chk1 and Chk2) in addition to downregulation of cell division cycle 25C (Cdc25C). Comparable experiments performed with other CGs (digitoxin and digoxin) in this study showed similar . . .
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