The mechanochemistry of copper reports on the directionality of unfolding in model cupredoxin proteins

HIGHLIGHTS

  • who: Amy E. M. Beedle from the WC R LS, CNRS, Institut de Biologie Physico-Chimique, PSL Research University, Laboratoire de Biochimie Théorique, Paris, France. have published the research work: The mechanochemistry of copper reports on the directionality of unfolding in model cupredoxin proteins, in the Journal: Cys 89 of 24/Dec/2014
  • what: Using the nanomechanical properties of the native copper centre as a structurally embedded molecular reporter the authors demonstrate that both proteins unfold via two independent competing pathways. The authors show that the protein can stochastically unfold along either the N . . .

     

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