The mesenchymal compartment in myelodysplastic syndrome: its role in the pathogenesis of the disorder and its therapeutic targeting

HIGHLIGHTS

  • who: Charalampos G. Pontikoglou and colleagues from the University of Patras, Greece have published the research work: The mesenchymal compartment in myelodysplastic syndrome: Its role in the pathogenesis of the disorder and its therapeutic targeting, in the Journal: (JOURNAL)
  • what: In the present review, the authors will attempt to summarize existing knowledge provided by in_vitro studies and mouse models supporting the notion of an impaired BM-MSC compartment in MDS and discuss its contribution in the pathogenesis of the disorder.

SUMMARY

    Within this context, cultured MDS-derived BM-MSCs have been . . .

     

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