The metabolic enzyme fructose-1,6-bisphosphate aldolase acts as a transcriptional regulator in pathogenic francisella

HIGHLIGHTS

  • who: Jason Ziveri from the CNRS have published the article: The metabolic enzyme fructose-1,6-bisphosphate aldolase acts as a transcriptional regulator in pathogenic Francisella, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
  • what: The authors show that the gene fba is dispensable for Francisella survival and growth under defined conditions, and appears to play a regulatory role in pathogenesis. The authors focused here on the role of the FBA in Francisella pathogenesis. The authors show here that FBA is not involved in phagosomal escape but is critical for cytosolic multiplication in the presence of . . .

     

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