The metabolic syndrome- associated small g protein arl15 plays a role in adipocyte differentiation and adiponectin secretion

HIGHLIGHTS

• who: Nuno Rocha from the Genetic studies, (NM_019087.2) was screened in a total of , individuals ascertained by severe insulin resistance and, controls, using several different sequencing approaches (see Supplementary Information for details of cohorts studied and sequencing techniques). All rare , alleles reported were verified in non-amplified genomic DNA using Sanger sequencing. For assessment of , exon , splicing from whole-blood RNA see Supplementary Information. Human imaging and physiological studies. Body composition was assessed using Lunar Prodigy dual-energy, ray absorptiometry (DEXA, GE Lunar). Hepatic triglyceride was assessed either using proton magnetic resonance spectroscopy on a Siemens . . .
  

   

  

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