The metal chaperone protein mtma plays important roles in antifungal drug susceptibility in aspergillus fumigatus

HIGHLIGHTS

  • who: ufeffPengfeiufeff ufeffZhaiufeff and collaborators from the (CAMS), China Tel Aviv University have published the paper: The metal chaperone protein MtmA plays important roles in antifungal drug susceptibility in ufeffAspergillus fumigatusufeff, in the Journal: (JOURNAL)
  • what: The study shows that mitochondria-localized MtmA is critical for antifungal drug resistance involving drug efflux pumps that depend on the Ca2+ signaling system.
  • how: For the construction of GFP-tagged strains the authors used a homologous recombination approach in which the stop codon of the target gene was replaced with a fusion fragment of GFP + pyrG . . .

     

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