The methyltransferase domain of dengue virus protein ns5 ensures efficient rna synthesis initiation and elongation by the polymerase domain

HIGHLIGHTS

• who: NS et al. from the Aix-Marseille Université, AFMB UMR, Marseille, France and , CNRS, AFMB UMR, Marseille, France have published the research: The methyltransferase domain of dengue virus protein NS5 ensures efficient RNA synthesis initiation and elongation by the polymerase domain, in the Journal: (JOURNAL)
• what: The authors show that NS5-MTase ensures efficient RdRp activity by stimulating the de novo initiation and the elongation phase. The authors investigate the regulation of the RdRp activity of the polymerase domain of protein NS5 of dengue virus (DENV), by the NS5 methyltransferase domain. The authors investigated . . .
  

   

  

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