The microbial metabolite p-cresol induces autistic-like behaviors in mice by remodeling the gut microbiota

HIGHLIGHTS

• who: Patricia Bermudez-Martin from the Institut de Pharmacologie Moléculaire et Cellulaire, Centre National de la Valbonne, France have published the Article: The microbial metabolite p-Cresol induces autistic-like behaviors in mice by remodeling the gut microbiota, in the Journal: (JOURNAL)
• what: The authors show that mice chronically exposed to p-Cresol presented social behavior deficits, stereotyped/perseverative behaviors, changes in microbiota composition, and elevated p-Cresol levels. Frequent ASD comorbidities are hyperactivity, ID, and anxiety disorder and the authors show that related behavioral domains (locomotor activity, cognition, anxiety) are not impacted by . . .
  

   

  

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