The microrna cluster c19mc confers differentiation potential into trophoblast lineages upon human pluripotent stem cells

HIGHLIGHTS

• who: Norio Kobayashi from the Tohoku University of Medicine, Sendai, Japan have published the research: The microRNA cluster C19MC confers differentiation potential into trophoblast lineages upon human pluripotent stem cells, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
• what: The authors show that nau00efve hES cells can differentiate into hTS cells, but primed hES cells cannot. Considering that most gDMRs were hypomethylated in hTSLnau00efve cells but these cells still retain proliferation and differentiation potentials comparable to hTS cells, the authors focused on gDMRs that were hypermethylated in hTSLprimed cells but not in hTSLnau00efve and hTS cells . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or E-mail:

  If you don't have an account, you can create one here.