The mir-15b-smurf2-hsp27 axis promotes pulmonary fibrosis

HIGHLIGHTS

• who: Seulgi Jeon from the Graduate School of Pharmaceutical Sciences, Ewha Womans University, Ewhayeodaeu2011gil, Seodaemunu2011gu, Seoul, Republic of Korea have published the research: The miR-15b-Smurf2-HSP27 axis promotes pulmonary fibrosis, in the Journal: (JOURNAL)
• what: Using this model, mice were subjected to a single high-dose of 75 Gy IR, and lung tissues were collected on weeks 1, 2, 4, 6, and 12 to identify the pathological changes during lung fibrosis development (Fig 1A). In expansion of previous results that HSP27 activated NFkB by binding with IkBu03b1, the authors investigate whether the phospho . . .
  

   

  

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